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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA12
All Species:
15.15
Human Site:
T2577
Identified Species:
41.67
UniProt:
Q86UK0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK0
NP_056472.2
2595
293237
T2577
K
S
Y
E
T
A
D
T
S
S
Q
G
S
T
I
Chimpanzee
Pan troglodytes
XP_516070
2595
293284
T2577
K
S
Y
E
T
A
D
T
S
S
Q
G
S
T
V
Rhesus Macaque
Macaca mulatta
XP_001084970
2600
294020
T2582
K
S
Y
E
T
A
D
T
S
S
Q
G
S
T
I
Dog
Lupus familis
XP_536058
2594
293583
T2576
K
S
Y
E
T
A
D
T
S
S
Q
G
S
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5SSE9
5034
568879
F5017
E
Q
L
Q
T
P
C
F
P
V
D
S
P
S
T
Rat
Rattus norvegicus
Q9ESR9
2434
270910
I2417
D
T
E
D
E
G
L
I
S
F
E
E
E
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
V2249
K
N
Q
T
V
V
D
V
A
I
L
T
S
F
L
Chicken
Gallus gallus
XP_421867
3822
432025
A3800
A
D
P
D
G
M
D
A
G
P
D
V
T
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686632
3644
404365
T3625
F
A
T
A
K
V
D
T
D
G
L
E
A
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
91.9
N.A.
22.6
22.8
N.A.
32.4
42.3
N.A.
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.3
96.1
N.A.
34
41.6
N.A.
53.3
54.7
N.A.
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
6.6
6.6
N.A.
20
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
40
26.6
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
12
0
45
0
12
12
0
0
0
12
0
12
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
23
0
0
78
0
12
0
23
0
0
0
12
% D
% Glu:
12
0
12
45
12
0
0
0
0
0
12
23
12
0
12
% E
% Phe:
12
0
0
0
0
0
0
12
0
12
0
0
0
12
0
% F
% Gly:
0
0
0
0
12
12
0
0
12
12
0
45
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
34
% I
% Lys:
56
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
12
0
0
0
23
0
0
0
12
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
12
0
0
12
12
0
0
12
0
0
% P
% Gln:
0
12
12
12
0
0
0
0
0
0
45
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% R
% Ser:
0
45
0
0
0
0
0
0
56
45
0
12
56
23
0
% S
% Thr:
0
12
12
12
56
0
0
56
0
0
0
12
12
56
12
% T
% Val:
0
0
0
0
12
23
0
12
0
12
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _